Dino

Acetyl Coenzyme A Trilithium Salt Trihydrate

Acetyl Coenzyme A Trilithium Salt Trihydrate

Synonyms Acetyl-CoA trilithium salt ; Acetyl-CoA; Acetyl-S-CoA Li3; Acetyl CoA Lithium; Acetyl-S-CoA Lithium

CAS Number: 75520-41-1 Molecular Formula: C23H35Li3N7O17P3S·3H2O Molecular Weight: 815.502 g/mol

EC Number: 200-790-9 MDL Number: MFCD00167406

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SKU 02100490-CF
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Description

Product Description

Acetyl Coenzyme A Trilithium Salt Trihydrate

Application Notes

Acetyl coenzyme A is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. It is a positive regulator of pyruvate carboxylase. It is a percursor of the neurotransmitter acetylcholine.The acetic acid moiety which is bound by a high-energy bond (free energy 34.3 kJ/mol) to the -SH group of coenzyme A is a precursor to fatty acids, steroids and other naturally occurring compounds, such as terpenes and acetogenins present in plants. The biosynthetic pathways for acetyl-CoA have been published.In the transfer reaction by acetyl-CoA of the C2 acetyl fragment, either the carboxyl group or the methyl group may react (electrophilic vs. nucleophilic reaction, respectively).

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Cofactor

Specifications
SKU 02100490-CF
Application Notes Acetyl coenzyme A is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. It is a positive regulator of pyruvate carboxylase. It is a percursor of the neurotransmitter acetylcholine.The acetic acid moiety which is bound by a high-energy bond (free energy 34.3 kJ/mol) to the -SH group of coenzyme A is a precursor to fatty acids, steroids and other naturally occurring compounds, such as terpenes and acetogenins present in plants. The biosynthetic pathways for acetyl-CoA have been published.In the transfer reaction by acetyl-CoA of the C2 acetyl fragment, either the carboxyl group or the methyl group may react (electrophilic vs. nucleophilic reaction, respectively).
Biochemical Physiological Actions Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. It is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.
EC Number 200-790-9
Extinction Coefficient EM:(260 nm): 16,400 (water) , (259): 15,400 (0.1 M PO4 buffer, pH 7) , (232 nm): 8,700 (water) (Lit.)
Format powder
Hazard Statements H315-H319-H335
Applications Cofactor
Molecular Formula C23H35Li3N7O17P3S·3H2O
Molecular Weight 815.502 g/mol
Personal Protective Equipment Dust mask , Eyeshields, Gloves
Physical Appearance White Powder
Product Families Description Acetyl coenzyme A
Product Overview Acetyl Coenzyme A Trilithium Salt Trihydrate
Purity ≥92%
Safety Symbol GHS07
Storage and Handling -20 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
UV Visible Absorbance λ max (0.1N HCl) : 258 ± 4 nm