Okadaic Acid Sodium Salt

Okadaic Acid Sodium Salt

Synonyms OA; 9,10-deepithio-9,10-didehydroacanthifolicin

CAS Number: 78111-17-8 Molecular Formula: C44H67O13Na Molecular Weight: 805.015 g/mol

MDL Number: MFCD00210208

Packaging size: 100 μg

SKU 0215897480
Price:
$550.20
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Description

Product Description

Okadaic Acid Sodium Salt

Application Notes

Okadaic acid has been used to study various cellular processes such as the cell cycle and apoptosis including microtubule organization and tau hosphorylation. This phosphatase inhibitor has also played a role in the study of nitric oxide metabolism and calcium signaling. In addition, okadaic acid has been shown to activate transcription of the Cox-2 gene, disrupt golgi, arrest transport in the rough endoplasmic reticulum, and affect neurotransmitter release.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Inhibitor of type 1 and 2A protein phosphatases||Tumor promotor

Specifications
SKU 0215897480
Application Notes Okadaic acid has been used to study various cellular processes such as the cell cycle and apoptosis including microtubule organization and tau hosphorylation. This phosphatase inhibitor has also played a role in the study of nitric oxide metabolism and calcium signaling. In addition, okadaic acid has been shown to activate transcription of the Cox-2 gene, disrupt golgi, arrest transport in the rough endoplasmic reticulum, and affect neurotransmitter release.
Biochemical Physiological Actions Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases.
Hazard Statements H301-H311-H315-H331
Applications Inhibitor of type 1 and 2A protein phosphatases||Tumor promotor
Melting Point 171-175 deg C; 164-166 deg C
Molecular Formula C44H67O13Na
Molecular Weight 805.015 g/mol
Pack Size 100 μg
Preparation Method Preparation: Isolated from cultured Prorocentrum concavum by preparative flash, medium pressure and high performance liquid chromatography. Salf form generated in aqueous sodium hydroxide methanol solution.
Product Families Description Okadaic acid sodium salt
Product Overview Okadaic Acid Sodium Salt
Purity ≥98%
RTECS Number AA8227800
Safety Symbol GHS06
Solubility Readily soluble in many organic solvents, degrading in acid or base.
Source Prorocentrum concavum
Storage and Handling Store at -20 °C. Store Under Nitrogen.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.