Veratridine

Veratridine

Synonyms 4,9-Epoxycevane-3, 4, 12, 14, 16, 17, 20-Heptol-3-(3, 4-Dimethoxybenzoate); 3-Veratroylveracevine; (3β, 4α,16β)-4,9-epoxycevane- 3, 4, 12, 14, 16, 17, 20-heptol 3-(3,4-dimethoxybenoate)

CAS Number: 71-62-5 Molecular Formula: C36H51NO11 Molecular Weight: 673.8 g/mol

Beilstein Registry Number: 78875 EC Number: 200-758-4 MDL Number: MFCD00082515

Packaging size: 10 mg

SKU 0215900710
Price:
$175.15
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Description

Product Description

Veratridine

Application Notes

It has been used as an insecticide, acting as a paralytic agent with higher toxicity to insects than to mammals. It is also used to increase membrane sodium permeability. It has been used to study Na+ channel blockers such as vincamine and vincanol by inducing Na+ channels in the presence and absence of the drugs being tested.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Alkaloid

Specifications
SKU 0215900710
Application Notes It has been used as an insecticide, acting as a paralytic agent with higher toxicity to insects than to mammals. It is also used to increase membrane sodium permeability. It has been used to study Na+ channel blockers such as vincamine and vincanol by inducing Na+ channels in the presence and absence of the drugs being tested.
Beilstein Registry Number 78875
Biochemical Physiological Actions Opens voltage-dependent Na+ channels and prevents their inactivation. This, in turn, opens voltage-activated calcium channels, thus increasing intracellular calcium content and inducing neurotransmitter release. Alkaloid neurotoxin which depolarizes excitable tissue. Veratridine is cytotoxic to chromaffin cells in vitro.
EC Number 200-758-4
Format powder
Hazard Statements H300-H310-H315-H319-H330-H335-H361-H373-H412
Applications Alkaloid
Melting Point 180 DEG C
Molecular Formula C36H51NO11
Molecular Weight 673.8 g/mol
Optical Rotation +4.9° (25 mg/mL, ethanol, 25°C(Lit.)
Pack Size 10 mg
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves, respirator cartridges
Physical Appearance White Powder
Product Families Description Veratridine
Product Overview Veratridine
Purity ≥97%
RTECS Number YX5600000
Safety Symbol GHS06, GHS08
Solubility SOL IN <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/WATER">WATER</a>; SLIGHTLY SOL IN ETHER
Storage and Handling Store at -20 °C.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
UV Visible Absorbance 262 nm (ethanol)(Lit.)