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Poly-L-Lysine Hydrobromide

Poly-L-Lysine Hydrobromide

Synonyms PDL HBr

CAS Number: 25988-63-0 Molecular Formula: (C6H13N2OBr)n Molecular Weight: 402.54 g/mol

MDL Number: MFCD00237230

Packaging size: 5 mg

SKU 0219454305
Price:
$60.60
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Description

Product Description

Poly-L-Lysine Hydrobromide

Application Notes

Poly-L-lysine is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates. Polymers of both D- and L-lysine are used to coat slides. However, certain cells can digest poly-L-lysine; in this situation, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine. The lower molecular weight poly-lysine (30,000-70,000) is easier to use because it is less viscous in solution; however, the higher molecular weights of poly-lysine have more attachement sites per molecule available to the cells. A compromise between the easier to use lower molecular weight products and the extremely viscous higher molecular weights would be the products in the range of 70,000-150,000.Other applications of Poly-L-lysine include Conjugation to methotrexate for increased drug transport,Microencapsulation of islets ,Use in simple reproducible procedure for chromosomal preparations from a variety of tissues,Immobilation of living cells in biocompatible semipermeable microcapsules,In the preparation of polycationic beads,Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Attachment factor for tissue culture.

Specifications
SKU 0219454305
Application Notes Poly-L-lysine is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates. Polymers of both D- and L-lysine are used to coat slides. However, certain cells can digest poly-L-lysine; in this situation, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine. The lower molecular weight poly-lysine (30,000-70,000) is easier to use because it is less viscous in solution; however, the higher molecular weights of poly-lysine have more attachement sites per molecule available to the cells. A compromise between the easier to use lower molecular weight products and the extremely viscous higher molecular weights would be the products in the range of 70,000-150,000.Other applications of Poly-L-lysine include Conjugation to methotrexate for increased drug transport,Microencapsulation of islets ,Use in simple reproducible procedure for chromosomal preparations from a variety of tissues,Immobilation of living cells in biocompatible semipermeable microcapsules,In the preparation of polycationic beads,Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.
Format powder
Grade Cell Culture Reagent; γ-irradiated
Applications Attachment factor for tissue culture.
Molecular Formula (C6H13N2OBr)n
Molecular Weight 402.54 g/mol
Pack Size 5 mg
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance Beige Powder
Product Families Description Poly-L-lysine hydrobromide
Product Overview Poly-L-Lysine Hydrobromide
Sterility γ-Irradiated
Storage and Handling -20 °C
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.