Dino

Prostaglandin E2

Prostaglandin E2

Synonyms [5Z,11a,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; PGE2; Dinoprostone

CAS Number: 363-24-6 Molecular Formula: C20H32O5 Molecular Weight: 352.471 g/mol

Beilstein Registry Number: 4709356 EC Number: 206-656-6 MDL Number: MFCD00077861

Packaging size: 1 mg

SKU 0219457601
Price:
$236.05
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Description

Product Description

Prostaglandin E2

Application Notes

Prostaglandin E2 is use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Study of prostaglandin regulated cell signaling and gene regulation

Specifications
SKU 0219457601
Application Notes Prostaglandin E2 is use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation.
Beilstein Registry Number 4709356
Biochemical Physiological Actions Most biologically active prostaglandin. PGE2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation; regulates adenylyl cyclase. Tumor cells that over-express cyclooxygenase 2 display increased invasiveness, angiogenesis, and resistance to apoptosis that may be due to the PGE2-induced expression of angiogenic factors and stabilization of the anti-apoptotic protein, survivin.The effect of PGE2 on the immune system is mixed. It inhibits T cell activation in vitro, suggesting it is an immunosuppressant. However, in vivo, it appears to effect expansion of the Th17 subset and differentiation of the Th1 subset of T helper cells, marking it as an immunoactivator.
Certifications gamma-Irradiated
EC Number 206-656-6
Format solid
Grade γ-Irradiated
Hazard Statements H302-H360
Applications Study of prostaglandin regulated cell signaling and gene regulation
Melting Point 67 °C
Molecular Formula C20H32O5
Molecular Weight 352.471 g/mol
Pack Size 1 mg
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge,respirator filter
Physical Appearance White Solid
Product Families Description Prostaglandin E2
Product Overview Prostaglandin E2
Purity ≥99%
RTECS Number UK8000000
Safety Symbol GHS07, GHS08
Solubility Water Solubility58.1 mg/L
Sterility γ-Irradiated
Storage and Handling -20 °C
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.